Collection includes materials related southern California tourism, the Mission Revival movement, peace movement (1st half 20th century, citrus industry, and materials related to specific collections,including fine art, statuary, bells, crosses, dolls, aviation, Native American basketry, and Asian arts.

The Mojave Desert Archives preserves the history of transcontinental travel to the Los Angeles region through the Mojave Desert of eastern California. Route 66, National Old Trails Road, the Mojave Wagon Road, the Santa Fe Railway (now BNSF), Union Pacific Railroad, and Interstate highways were and are major transit routes through the desert terminating in the Los Angeles basin.

To share and make known the organization's significant archive and collections of San Fernando Valley history. SFVHS serves as caretaker of the Andres Pico Adobe historic site in Mission Hills as well as the Pioneer Cemetery in Sylmar.

Collections of the organization document the history of the Sisters in Los Angeles and California from 1926-present. Particular emphasis is given to Hungarian immigrant experience and social services with Hispanic neighborhoods. Archives also include records which reflect the activities of the Social Service Auxiliary and Juniors of Social Service.