The materials of the Regional History Collection document 100 years of Southern California history in various formats. The collection was founded in the mid-1970s as a repository for the papers of Southern Californian political figures, among them Governor Jerry Brown Jr., Congresswoman Yvonne Brathwaite Burke; and Congressmen Alphonso Bell, Chet Holifield, Craig Hosmer, and Gordon McDonough.

As the only collecting institution focused solely on the art, craft, and history of Hollywood writers and their labor union, the Writers Guild Foundation Library & Archive are vividlly relevant to the creative and business communities of Los Angeles. The holdings document a rich facet of Los Angeles culture in relation to the role of writers in the entertainment industry.